Molecular markers in well-differentiated thyroid cancer
نویسندگان
چکیده
منابع مشابه
Thyroid hormone replacement one day before 131I therapy in patients with well-differentiated thyroid cancer
Objective: The current study aimed to determine the efficacy of radioiodine-131 (131I) ablation therapy with thyroid hormone replacement one day before 131I administration in patients with well-differentiated thyroid cancer (DTC). Methods: This retrospective study included 29 patients who underwent 131I therapies twice for DTC during 6-12 months. Since all the patients obviously had residual l...
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Genetic and epigenetic alterations have been associated with cancer development and progression. Important epigenetic modifications include posttranslational histone changes, covalent modifications of DNA bases and non-coding RNAs. Welldifferentiated thyroid carcinomas comprise papillary and follicular carcinomas, the most common subtypes. Methylation of thyroid-specific genes, including NIS an...
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Copyright: © 2012 Barczyński M. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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Thyroid cancer is a common endocrine malignancy. The tumorigenesis of thyroid tumours has been identified in recent years, including numerous genetic alterations and several major signalling pathways. However, the molecular mechanisms involved in thyroid cancer metastasis remain controversial. Studies in thyroid cancer metastasis suggested that reactivation of several pathways, including epithe...
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Four proto-oncogenes commonly associated with well-differentiated thyroid carcinoma, rearranged during transfection (RET)/papillary thyroid cancer, BRAF, RAS, and PAX8/peroxisome proliferator activated receptor-γ, may carry diagnostic and prognostic significance. These oncogenes can be used to improve the diagnosis and management of well-differentiated thyroid carcinoma. Limited therapeutic opt...
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ژورنال
عنوان ژورنال: European Archives of Oto-Rhino-Laryngology
سال: 2018
ISSN: 0937-4477,1434-4726
DOI: 10.1007/s00405-018-4944-1